Fig. 9: The XVK motif is conserved in other ArfGAPs.
From: An active allosteric mechanism in ASAP1-mediated Arf1 GTP hydrolysis redefines PH domain function
(Top left) Schematic organization of ASAP, ACAP, AGAP and ARAP family PZA domains. (right) Structural alignment of ASAP1 PH (yellow) with ACAP1 (red), AGAP1 (blue) and ARAP1 (green) PH domains highlighting the conservation of the XVK motif in each family. (bottom left) Structural alignment of their amino acid sequences centered around the XVK motif. All images created using Chimera56. Source data are provided as a Source data file.
