Fig. 1: The impact of maternal Zika virus infection on pregnancy outcomes and offspring growth.
From: Prenatal exposure to Zika virus shapes offspring neutrophil function in a sex-specific manner
a Gestational length (n = 18 control, 16 ZIKV) and litter size (n = 17 control, 14 ZIKV). b Average percentage of female and male fetuses at E12.5, E17.5, and postnatally. c, d Implantations and resorptions at E12.5 (n = 10 control, 8 ZIKV) and E17.5 (n = 10/group). e Placenta weight and fetal weight at E12.5 by sex (n = 21 female, 17 male placentas/fetuses from 5 control dams; n = 25 female, 33 male placentas/fetuses from 7 ZIKV dams). f Placenta weight and fetal weight at E17.5 by sex (n = 32 female, 22 male placentas/fetuses from 7 control dams; n = 24 female, 34 male placentas/fetuses from 7 ZIKV dams). g Representative placenta and fetus image. h CRL at E12.5 (n = 20 female, 16 male fetuses from 5 control dams; n = 15 female, 25 male fetuses from 7 ZIKV dams) and E17.5 (n = 32 female, 23 male fetuses from 7 control dams; n = 24 female, 34 male fetuses from 7 ZIKV dams) by sex. i OFD at E12.5 (n = 21 female, 16 male fetuses from 5 control dams; n = 16 female, 25 male fetuses from 7 ZIKV dams) and E17.5 (n = 32 female, 23 male fetuses from 7 control dams; n = 24 female, 34 male fetuses from 7 ZIKV dams) by sex. j Postnatal body weight at day 35 (n = 29 female, 30 male offspring from 7 control dams; n = 39 female, 38 male offspring from 10 ZIKV dams) by sex. Data are mean ± SD. Two-sided Student’s t-test (a, c, d) and two-way ANOVA with Ĺ Ădák’s multiple comparisons (e, f, h, i, j). M male, F female, OFD occipital–frontal diameter, CRL crown–rump length. Source data provided.
