Fig. 4: Individual heterogeneity of regional surface area after preterm birth across cohorts. | Nature Communications

Fig. 4: Individual heterogeneity of regional surface area after preterm birth across cohorts.

From: Heterogeneous, temporally consistent, and plastic brain development after preterm birth

Fig. 4

a Surface area (SA) average dysmaturation outcome after preterm birth estimated by linear regression models correcting for age and sex (pFDR <0.05). Results are shown for neonates (dHCP), children (ABCD-10), and adults (BLS-26 and BLS-38). b The percentage of preterm (PT) and full-term (FT) subjects sharing an extranormal deviation in any cortical region. Not more than 30% of subjects overlap in any region, demonstrating that spatial heterogeneity between individuals is also evident for regional SA development after preterm birth. As regional percentile SA trajectories for the entorhinal cortex were not available from the normative model, no subjects of any cohort shows extranormal deviations in that region. c Distribution of averaged correlation coefficients of binarized extranormal deviation profiles for each subject with all others. See Supplementary Table S1 for region abbreviations and number encoding. Source data are provided as a Source Data file.

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