Fig. 7: Temporal consistency of IBAP cellular underpinnings.
From: Heterogeneous, temporally consistent, and plastic brain development after preterm birth
a Regional Spearman correlation matrix of cortical thickness (CTh) individual brain abnormality patterns (IBAPs) from preterm adults aged 26 years (vertical) with mean expression profile of eight brain cell types (horizontal). CTh IBAPs of three example subjects are plotted for illustration purposes. Investigated cell types were astrocytes (Astro), endothelial cells (Endo), microglia (Micro), excitatory neurons (Neuro-Ex), inhibitory neurons (Neuro-In), oligodendrocytes (Oligo), oligodendrocyte precursors (OPC), and pericytes (Per). b Spearman correlation coefficients for the association between astrocytes, endothelial cells, oligodendrocytes, and OPCs, with individual CTh deviations were significantly related to gestational age in preterm adults (p < 0.05, two-sided). Orange lines and shades represent the linear regression line with 95% confidence intervals based on 10,000 bootstrap resamples. See Supplementary Table S5 and Source Data files for Source Data and exact p values.
