Fig. 4: Scope of the anti-selective carboboration reaction. | Nature Communications

Fig. 4: Scope of the anti-selective carboboration reaction.

From: Catalyst-controlled stereodivergent synthesis of polysubstituted alkenes

Fig. 4

General reaction conditions: alkyne (0.4 mmol, 1.0 equiv.), B2pin2 (2.0 equiv.), alkyl bromide (2.0 equiv.), NiCl2·DME (5 mol%), L8 (5 mol%), LiOMe (2.0 equiv.) in 1,4-dioxane (0.2 M) was at 40 oC stirred for 12 h. The given isolated yields refer to the single isomeric product; anti:syn selectivities were determined by GC analysis of the crude reaction mixtures. a L5 was used.

Back to article page