Fig. 7: In vitro biocompatible evaluation of Cu/CN. | Nature Communications

Fig. 7: In vitro biocompatible evaluation of Cu/CN.

From: Cu single-atom embedded g-C3N4 nanosheets rehabilitate multidrug-resistant bacteria infected diabetic wounds via photoswitchable cascade reaction

Fig. 7

a Fluorescence images of 3T3 fibroblast cells cultured with PBS, glucose, CN700 and Cu/CN after 24 h. b Cell viability (n = 3 independent experiments) of the CN700 and Cu/CN. c Hemolysis ratio (n = 3 independent experiments) of the CN700 and Cu/CN. d Cell migration of HUVEC cells in the control and the different groups at 0, 24, and 48 h. e The cellular migration after various treatments for different time periods was identified by drawing the green shadow at the edge of cells in (d), and calculate the area of cell migration (n = 3 independent experiments). P values were calculated by the one-way ANOVA method. b ns (p > 0.05): p = 0.1194, Cu/CN vs. control. d ns (p > 0.05): p = 0.4922, Cu/CN vs. Tris-HCl. e ****(p < 0.0001): Cu/CN vs. PBS for 24 h, **(p < 0.01): p = 0.0028, CN700 vs. PBS for 24 h; ****(p < 0.0001): Cu/CN vs. PBS for 48 h, **(p < 0.05): p = 0.0356, CN700 vs. PBS for 48 h. Data were presented as mean value ± SD. The experiments for (b, c, e) were repeated three times independently with similar results.

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