Extended Data Fig. 7: TOP1 regulates mTOR and cell cycle gene expression in response to Glc.
From: TOP1α fine-tunes TOR-PLT2 to maintain root tip homeostasis in response to sugars
a, The cell viability of human NSCLC cell line HCC827 under the indicated treatments. Data represent mean ± s.d. of 3 biological repeats. Student’s t test (two-tailed). b, RT-qPCR of mTOR and cell cycle gene expression in HCC827 under the indicated treatments. Gene expression in untreated cells in 5 mM Glc was set to 1. Data represent mean ± s.d. of 3 biological repeats. Student’s t test (two-tailed). GAPDH served as negative control.
