Extended Data Fig. 1: Dot plot matrix of selected proteins from the AP/TPC interactome.

Quantitative dot plot matrix covering core AP/TPC subunits and a selection of proteins linked to endocytosis/vesicle trafficking. The colour hue of the nodes corresponds with the abundance of each prey in a given experiment, calculated by subtracting the average normalized spectral abundance factor (NSAF) in the control dataset from the average NSAF (bait) of each prey [NSAF (bait - ctrl.)]. The size of the dots reflects the relative abundance of each prey over the different experiments. The identification of each bait protein is shown by an asterisk.