Fig. 5 | npj Aging and Mechanisms of Disease

Fig. 5

From: Blocking negative effects of senescence in human skin fibroblasts with a plant extract

Fig. 5

Analysis of pathways and upstream regulators affected by 1201 treatment. a List of selected canonical pathways and b upstream regulators derived from Ingenuity pathway analysis of RNA-Seq data (for complete lists refer to Supplementary Tables S2 and S3). c Pathway enrichment analysis of genes upregulated by 1201 in both, Q and SIPS cells, and d of genes downregulated by 1201 in SIPS cells. Gene expression levels were derived from RNA-Seq data. From a to d, data represent the average of three experiments

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