Fig. 5
From: Daily blue-light exposure shortens lifespan and causes brain neurodegeneration in Drosophila
Flies lacking retina show reduced lifespan and brain neurodegeneration in blue light. a Lifespan of eyes-absent mutant (eya2) flies is significantly reduced in B:D compared with D:D (Log-rank test, p < 0.0001 for males and females), but is similar in W–B:D conditions (N = 100 for each light condition). b Aged eya2 males show a significant reduction in the average vertical climbing ability in B:D compared with D:D (unpaired t test, p = 0.0009). c Representative brain sections showing brain vacuoles (red arrowheads) in 52-day-old eya2 males in D:D and B:D. d The average area of brain vacuolization of 52-day-old eya2 males was significantly increased in B:D compared with D:D (unpaired t test, p = 0.0352). Numbers above bars indicate the sample size in each light condition. Error bars show SEM
