Table 2 Comparison of salient features between the proposed method (PoCT NMR) benchmarking against the gold standard, urinary F2-IsoP.

From: Molecular phenotyping of oxidative stress in diabetes mellitus with point-of-care NMR system

 

Proposed method

Gold standard

Biological liquid

RBC

Urine (isoprostance molecules)

Mechanism

Glutathione depletion

Lipid peroxidation

Method

Direct

Indirect

Functional test

Yes

No

Instrumentation

POCT NMR

LC/MS

Portability

Yes

No

Analysis time

Rapid (min)

Hours