Table 1 Healthy ageing status association statistics of common genome-wide hits identified in the SCHS study.

From: Genetic associations with healthy ageing among Chinese adults

      

SCHS Discovery

SCHS Replication

Meta-analysis

      

Case = 1489 / Control = 5721

Case = 129 / Control = 500

Case = 1618 / Control = 6221

 

Chromosome

Position

Nearest gene

TA

TAF

OR (95% Cl)

P

OR (95% Cl)

P

OR (95% Cl)

p

pQ

rs138499810

5

82019798

Intergenic

T

0.020

3.104 (2.067, 4.663)

4.82 × 10−8

3.670 (1.103, 12.213)

0.034

3.158 (2.148, 4.643)

4.94 × 10−9

0.796

rs117898573

2

142877484

LRP1B

T

0.029

2.626 (1.888, 3.651)

9.65 × 10−9

1.218 (0.451, 3.291)

0.697

2.433 (1.779. 3.327)

2.59 × 10−8

0.151

  1. Chr Chromosome, TA test allele, TAF test allele frequency, OR Odds ratio, Cl Confidence interval, pQ Cochran’s Q heterogeneity P value.
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