Table 1 Key Messages.

• Inappropriate polypharmacy is a significant public health challenge.

• Deprescribing is a safe and effective method of managing this issue.

• Deprescribing is a complex and nuanced process in a heterogenous group of patients.

• There are significant barriers such as time, education, and fear of adverse effects.

• To approach deprescribing successfully, there is a need for a collaborative multidisciplinary approach with open and effective communication.