Table 1 Baseline characteristics and oxidative stress descriptors by carbonyl tertile

From: Oxidative damage in the gastrocnemius predicts long-term survival in patients with peripheral artery disease

Variablea

All (N = 241)

Tertile 1 (N = 79)

Tertile 2 (N = 80)

Tertile 3 (N = 82)

P-valueb

Decedents, n(%)

99 (41.08)

6 (7.59)

34 (42.50)

59 (71.95)

0.001

Age (years)

64.39 ± 9.50; 63.48 (57.84,71.50)

63.44 ± 9.82; 63.48 (56.03, 71.40)

64.51 ± 9.29; 63.46 (57.41, 71.25)

65.17 ± 9.42; 63.51 (59.72, 73.55)

0.598

Male, n(%)

226 (93.78)

71 (89.87)

75 (93.75)

80 (97.56)

0.130

African American, n(%)

16 (6.64)

5 (6.33)

4 (5)

7 (8.54)

0.766

Area

4060.85 ± 1480.48; 3961.22 (2954.00, 5108.80)

4564.57 ± 1910.10; 4715.70 (3338.19, 5922.30)

3927.97 ± 1360.01; 3907.03 (2896.66, 5007.15)

3739.28 ± 1459.58; 3758.40 (2758.00, 4793.70)

0.001

BMI (kg/m2)

27.36 ± 5.77; 26.97 (23.85, 31.38)

27.87 ± 5.91; 28.40 (24.54, 31.53)

27.71 ± 5.92; 26.54 (23.60, 32.09)

26.54 ± 5.47; 25.94 (23.60, 30.73)

0.175

ABI

0.44 ± 0.34; 0.38 (0.12,0.65)

0.46 ± 0.34; 0.41 (0.12, 0.66)

0.47 ± 0.33; 0.40 (0.20, 0.75)

0.40 ± 0.35; 0.30 (0.10, 0.62)

0.178

Current/Former Smoker, n(%)

241 (70.95)

53 (67.09)

54(67.50)

64 (78.05)

0.219

CAD, n(%)

88 (36.51)

26 (32.91)

28 (35.00)

34 (41.46)

0.500

HTN, n(%)

180 (74.69)

56 (70.89)

60 (75.00)

64 (78.05)

0.578

Dyslipidemia, n(%)

138 (57.26)

46 (58.23)

46 (57.50)

46 (56.10)

0.962

Family History, n(%)

66 (27.73)

18 (23.38)

22 (27.5)

26 (32.10)

0.472

DM, n(%)

101(41.91)

22 (27.85)

35 (43.75)

44 (53.66)

0.004

Renal Failure, n(%)

28 (11.62)

8 (10.13)

6 (7.50)

14 (17.07)

0.145

Statins Use, n(%)

145 (60.17)

50 (63.29)

46 (57.5)

49 (59.76)

0.754

Claudication, n(%)

126 (52.28)

54 (68.35)

41 (51.25)

31 (37.80)

0.001

CLI, n(%)

115 (47.72)

25 (31.65)

39 (48.75)

51 (62.20)

0.001

  1. aContinuous variables summarized as mean ± SD, Median (IQR: Q1, Q3), and categorical variables as n(%).
  2. bP-values from the (nonparametric) ANOVA for continuous variables, and the Chi-square test for categorical variables
  3. HTN hypertension, BMI body mass index, ABI ankle-brachial index, CAD coronary artery disease, DM diabetes melitus, Family History family history of atherosclerotic arterial disease, Claudication peripheral artery disease (PAD) stage II, and CLI PAD Stages III/IV (Critical Limb Ischemia).
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