Fig. 2: Different routes of neuronal differentiation.
From: Strategies for modeling aging and age-related diseases
Schematic model depicting three ways of neuronal differentiation (generated in Bio-render). 1) Conventional route to reprogram IPSC from fibroblasts followed by subsequent differentiation into neurons. 2) Reprogramming of fibroblasts into neural stem cells (NSCs) followed by differentiation into neurons. 3) Direct transdifferentiation of fibroblasts to neurons.
