Fig. 6: Venn diagram showing the number of differentially expressed genes observed in kidney, liver, and spleen tissue in the interspecies comparison between Spalax and rat kept at normoxic conditions. | npj Aging

Fig. 6: Venn diagram showing the number of differentially expressed genes observed in kidney, liver, and spleen tissue in the interspecies comparison between Spalax and rat kept at normoxic conditions.

From: Adaptation of the Spalax galili transcriptome to hypoxia may underlie the complex phenotype featuring longevity and cancer resistance

Fig. 6

A Genes showing higher expression in Spalax than in rat. B Genes showing lower in Spalax than in rat. Criterion for differential expression was a value of padj < 0.05. The large number of genes, which are differentially expressed in all three tissues, indicates across-organ adaptations on the gene regulatory level in Spalax compared to rat.

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