Table 1 Characteristics of study subjects

From: Dysregulations of C1QA, C1QB, C1QC and C5AR1 as candidate biomarkers of vascular dementia

Characteristics

VCI group

control

P value

Age (years)

66.5 ± 5.1

65.2 ± 5.9

0.153

Percent women (%)

56.3

53.1

0.312

SBP (mmHg)

158.2 ± 32.4

150.7 ± 28.5

0.018

DBP (mmHg)

94.6 ± 20.3

86.3 ± 17.9

0.015

PP (mmHg)

57.3 ± 10.6

60.5 ± 14.2

0.205

WBC(×109/L)

6.2 ± 1.2

5.5 ± 1.3

0.007

RBC (×1012/L)

4.8 ± 0.5

4.8 ± 0.5

0.916

Hb (g/L)

148.5 ± 15.3

147.9 ± 15.2

0.855

NLR

1.9 ± 0.8

1.7 ± 0.7

0.351

FBG (mmol/L)

5.8 ± 0.7

5.7 ± 0.7

0.505

HbA1c (%)

5.8 ± 0.4

5.9 ± 0.5

0.716

TB(μmol/L)

13.3 ± 3.8

14.0 ± 4.6

0.521

TC (mmol/L)

5.5 ± 1.1

5.4 ± 0.9

0.424

TG (mmol/L)

1.8 ± 1.3

1.5 ± 0.9

0.287

LDL-C (mmol/L)

3.6 ± 1.0

3.3 ± 0.7

0.042

HDL-C (mmol/L)

1.4 ± 0.3

1.7 ± 0.5

<0.001

MoCA score

18.6 ± 3.3

28.5 ± 1.3

<0.001

C1QA (μg/mL)

224.1 ± 85.9

268.6 ± 93.0

0.008

C1QB (μg/mL)

162.9 ± 46.8

112.0 ± 41.8

<0.001

C1QC (ng/mL)

539.6 ± 138.5

457.1 ± 34.9

<0.001

C5AR1 (ng/mL)

190.6 ± 53.2

151.4 ± 61.7

<0.001

  1. VaD vascular dementia, SBP systolic blood pressure, DBP diastolic blood pressure, PP pulse pressure, WBC white blood cell, RBC red blood cell, Hb hemoglobin, NLR neutrophil to lymphocyte ratio, FBG fast blood glucose, HbA1c hemoglobin A1c, TB total bilirubin, TC total cholesterol, TG triglyceride, LDL-C low-density lipoprotein cholesterol, HDL-C low-density lipoprotein cholesterol, MoCA Montreal Cognitive Assessment.