Fig. 1: Anthropometric and calorie restriction characteristics of a subset of study participants (n = 26, 13 male, 13 female) are included in this report.

A A line chart with points depicts body weight at baseline, 12mo and 24mo. B A box and whisker plot, with a dotted line separating the individual 12mo intervals from the total study %CR. The plots depict %CR during each intervention period. Inset p-values in (A) were obtained from repeated-measures mixed models with time (months) as the repeated measure and participant as a random effect. Inset p-values in (B) were obtained from repeated-measures mixed models using time intervals as repeated measures and participant as a random effect.