Fig. 2: Transcriptional profiles recorded for biofilm-associated conditions exhibit a higher diversity than those recorded for planktonic conditions.
From: Parallel evolutionary paths to produce more than one Pseudomonas aeruginosa biofilm phenotype
a The multidimensional scaling plot (MDS) of transcriptional profiles of 77 clinical strains shows a higher divergence in biofilm conditions (BF; filled circles) as compared to planktonic conditions (PL; triangles). b Pairwise measurements of Euclidian distances and c the Pearson’s distance (Pearson correlation coefficient subtracted from 1 to describe the variance) between the samples of the two culture conditions (biofilm and planktonic) are depicted. Significance of the Wilcoxon’s rank sum-test is displayed as ****p < 0.0001. Boxplot elements are: center line—median; box limits—upper and lower quartiles; whiskers—1.5× interquartile range; points—outliers. d Clinical isolates show a broad range in the number of differentially expressed genes (biofilm versus planktonic). The number of core biofilm transcriptome genes present in each strain is displayed in dark red (upregulated in biofilms) and dark blue (downregulated in biofilms).
