Fig. 5: Biofilm cluster-specific isolates differ in their production of various virulence factors.
From: Parallel evolutionary paths to produce more than one Pseudomonas aeruginosa biofilm phenotype
a In vivo virulence using the Galleria mellonella model, b in vitro cytotoxicity on A549 epithelial cells, c intracellular second messenger c-di-GMP levels, d swimming motility, e twitching motility, f swarming motility, g pyocyanin production, h elastase secretion, and i protease production of selected isolates belonging to the three different biofilm clusters are depicted. Each dot represents one individual clinical isolate. Levels of statistical significance were calculated using Tukey’s HSD (honest significant difference) following analysis of variance (ANOVA) and are displayed as ****p < 0.0001, **p < 0.01, or *p < 0.05.
