Table 2 List of the top 30 most upregulated genes in H. pylori G27 grown in biofilm condition (cutoff ratio ≥1 log2 fold-change and P-value < 0.05) using RNA-seq analysis. These genes are all expressed to higher levels in the biofilm cells.

From: Genetic requirements and transcriptomics of Helicobacter pylori biofilm formation on abiotic and biotic surfaces

Name

Putative gene product

Fold-change

HPG27_166

Hypothetical protein

12.13

HPG27_979

VirC1

9.07

HPG27_970

VirB11-like

6.43

HPG27_1233

m6A methyltransferase

6.35

HPG27_969

Hypothetical protein

5.93

HPG27_1522

Hypothetical protein

4.72

HPG27_270

Chorismate mutase

4.59

HPG27_968

Hypothetical protein

4.46

HPG27_509

Glutamate racemase

3.92

HPG27_1066

m5C methyltransferase

3.89

HPG27_324

RluA, pseudouridine synthase D

3.57

HPG27_1059

Hypothetical protein

3.53

HPG27_335

Hypothetical protein

3.39

HPG27_269

LysA, diaminopimelate decarboxylase

3.29

HPG27_671

LptB, ABC transporter

3.26

HPG27_506

CagB, cag island protein B

3.18

HPG27_271

Hypothetical protein

3.17

HPG27_442

m5C methyltransferase

3.15

HPG27_834

Hypothetical protein

3.13

HPG27_669

Hypothetical protein

3.06

HPG27_1331

Hypothetical protein

2.97

HPG27_377

TsaB, tRNA A37 threonylcarbamoyladenosine modification protein

2.96

HPG27_72

PrfA, peptide chain release factor RF-1

2.96

HPG27_1241

Thiamine pyrophosphokinase

2.73

HPG27_652

AcxB, acetone carboxylase subunit alpha

2.69

HPG27_589

Hypothetical protein

2.68

HPG27_800

Hypothetical protein

2.63

HPG27_571

ABC transporter, permease

2.62

HPG27_47

HypAV, type II restriction enzyme

2.59

HPG27_1299

HpyAIV, type II restriction endonuclease

2.59

HPG27_660

Hypothetical protein

2.57