Table 1 Bacterial content from oral swabs.

From: Polymicrobial periodontal disease triggers a wide radius of effect and unique virome

 

P. gingivalis

T. denticola

T. forsythia

F. nucleatum

Total bacteria

Control

Infection

Control

Infection

Control

Infection

Control

Infection

Control

Infection

Baseline 1

16,981.09 ± 28,369.48

723.03 ± 407.71

1.18 ± 2.05

0.07 ± 0.07

8.43 ± 14.57

31.56 ± 23.59

59.47 ± 11.56

72.66 ± 28.24

553,248.72 ± 639,763.52

121,168.24 ± 80,829.30

(4:4; 100%)

(6:6; 100%)

(1:4; 25%)

(2:6; 33%)

(2:4; 50%)

(5:6; 83%)

(4:4; 100%)

(6:6; 100%)

(−)

(−)

Baseline 2

58.39 ± 85.52

77.71 ± 61.10

0.00 ± 0.00

1.03 ± 1.46

103.48 ± 54.06

151.63 ± 42.29

104.50 ± 36.60

149.37 ± 48.89

37,282.08 ± 16,477.93

30,052.84 ± 7,525.85

(6:6; 100%)

(6:6; 100%)

(0:6; 0%)

(2:6; 33%)

(6:6; 100%)

(6:6; 100%)

(6:6; 100%)

(6:6; 100%)

(−)

(−)

1 week

299.89 ± 100.69

4,077.78 ± 1,805.15

1.19 ± 1.87

7.26 ± 4.58

1,096.65 ± 832.67

8,935.11 ± 3,838.25

550.51 ± 232.78

4,547.68 ± 2,009.55

183,983.00 ± 115,301.42

92,192.86 ± 50,283.58

(5:5; 100%)

(5:5; 100%)

(2:5; 40%)

(4:5; 80%)

(5:5; 100%)

(5:5; 100%)

(5:5; 100%)

(5:5; 100%)

(−)

(−)

4 weeks

191.06 ± 68.67

15,943.21 ± 13,755.35

0.00 ± 0.00

0.00 ± 0.00

88.87 ± 75.33

21,464.59 ± 18,251.40

120.49 ± 29.79

12,066.57 ± 10,766.24

21,150.11 ± 5,938.39

746,180.73 ± 576,242.33

(6:6; 100%)

(6:6; 100%)

(0:6; 0%)

(0:6; 0%)

(6:6; 100%)

(6:6; 100%)

(6:6; 100%)

(6:6; 100%)

(−)

(−)

8 weeks

73.40 ± 66.95

728.94 ± 1,059.93

0.00 ± 0.00

10.62 ± 15.06

2,005.86 ± 2,431.41

27,481.09 ± 5,043.55

296.09 ± 212.52

10,280.58 ± 2,788.89

32,852.47 ± 12,385.56

204,945.44 ± 67,419.62

(6:6; 100%)

(6:6; 100%)

(0:6; 0%)

(2:6; 33%)

(6:6; 100%)

(6:6; 100%)

(6:6; 100%)

(6:6; 100%)

(−)

(−)

  1. Actual numbers of bacteria/swab (mean ± s.d.)
  2. (presence of periodontal pathogens in numbers of mice [%]).