Table 1 Baseline characteristics of the study participants.

From: Salivary dysbiosis in Sjögren’s syndrome and a commensal-mediated immunomodulatory effect of salivary gland epithelial cells

 

pSS patients

Healthy controls

Number of cases

8

16

Age (year, IQR)

58 (48–65)

59 (45–68)

Women (n, %)

8 (100)

16 (100)

Smoking (n, %)

0 (0)

0 (0)

Autoimmune diseases other than pSS (n, %)

0 (0)

0 (0)

Received immunomodulators/immunosuppressants or corticosteroids in last 3 months (n, %)

0 (0)

0 (0)

Received antibiotics in last 3 months (n, %)

0 (0)

0 (0)

Duration of clinically apparent xerostomia (months, IQR)

12 (11–36)

0 (0–0)

Sialoscintigraphy gradesa

<grade II (n, %)

3 (43)

NA

=grade II (n, %)

3 (43)

NA

>grade II (n, %)

1 (14)

NA

ESSDAI (point, IQR)

0 (0–4)

NA

Serology tests

ANA titer ≥ 1:160 (n, %)

2 (25)

NA

Positivity of anti-Ro (n, %)

4 (50)

NA

Positivity of anti-La (n, %)

2 (25)

NA

Positivity of RF (n, %)

2 (25)

NA

LSG biopsy focus score ≥1 (n, %)

4 (50)

NA

  1. IQR interquartile range, NA not applicable, pSS primary Sjögren’s syndrome, ESSDAI European League Against Rheumatism Sjögren’s syndrome disease activity index, LSG labial salivary gland, ANA antinuclear antibody, RF rheumatoid factor.
  2. aOne patient fulfilled the classification criteria of pSS without a sialoscintigraphy.