Fig. 2: Scanning electron microscopy (SEM) images of extracted mucosa from the middle ear of a mouse model of P. aeruginosa CSOM. | npj Biofilms and Microbiomes

Fig. 2: Scanning electron microscopy (SEM) images of extracted mucosa from the middle ear of a mouse model of P. aeruginosa CSOM.

From: Treatment with a neutrophil elastase inhibitor and ofloxacin reduces P. aeruginosa burden in a mouse model of chronic suppurative otitis media

Fig. 2

SEM images of extracted middle ear tissue. Neutrophils crowd mucosal surface after a biofilm begins to grow following inoculation with P. aeruginosa. Orange arrows indicate putative neutrophils on the mucosal surface. a SEM image taken from control middle ear mucosal surface. b SEM image taken from mucosa 1 d.p.i with PAO1. This experiment was repeated twice with highly similar results. C57BL/6J mice were inoculated with P. aeruginosa PAO1 or PBS one day following Eustachian tube occlusion and acute tympanic membrane perforation. Bar, 20 µm.

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