Fig. 6: Synergistic activity: Biofilm disruption assay using G. vaginalis ATCC14018, G. vaginalis UG860107 and G. vaginalis BUL001 pre-established biofilms.

Final concentrations of A CCB2M94_8, B CCB7.1, C CCB8.1, D CCB2.2 or E CCB4.1 ranged from 2.5 to 50 μg/ml, were used to disrupt biofilms. OD600 readings are the average of biological triplicates plus/minus their standard deviation. The asterisks in figures indicate levels of significance. p-values < 0.05 are represented by *, p-values < 0.01 are represented by **, p-values < 0.001 are represented by *** and p-values < 0.0001 are represented by ****. No statistical differences are represented by ns. Controls: MES corresponds to bacteria with MES buffer and control medium is the no bacterial control. p-values for ANOVA and Tukey tests.