Fig. 7: Polymicrobial biofilm disruption.

A Biofilm disruption assay using G. vaginalis ATCC14018 and A. vaginae UG71161 polymicrobial biofilms. The different endolysin candidates, metronidazole and clindamycin were used in a final concentration of 200 μg/ml. B Biofilm disruption assay using A. vaginae UG71161 biofilms. The different endolysin candidates, metronidazole and clindamycin were used in a final concentration of 200 μg/ml. OD600 readings are the average of biological triplicates plus/minus their standard deviation. The asterisks in figures indicate levels of significance. p-values < 0.05 are represented by *, p-values < 0.01 are represented by **, p-values < 0.001 are represented by *** and p-values < 0.0001 are represented by ****. No statistical differences are represented by ns. p-values for ANOVA and Tukey tests.