Table 4 MIC for five different endolysin candidates, metronidazole and clindamycin against vaginal lactobacilli and A. vaginae.
Endolysin/antibiotic | MIC (μg/ml) | ||||
|---|---|---|---|---|---|
L. jensenii CCUG35572 | L. gasseri CCUG4409 | L. crispatus CCUG42898 | L. iners CCUG38673 | A. vaginae UG71161 | |
CCB2M94_8 | ≥200 | ≥200 | ≥200 | ≥200 | ≥200 |
CCB7.1 | ≥200 | ≥200 | ≥200 | ≥200 | ≥200 |
CCB8.1 | ≥200 | ≥200 | ≥200 | ≥200 | ≥200 |
CCB2.2 | ≥200 | ≥200 | ≥200 | ≥200 | ≥200 |
CCB4.1 | ≥200 | ≥200 | ≥200 | ≥200 | ≥200 |
Metronidazole | ≥200 | ≥200 | ≥200 | ≥200 | ≥200 |
Clindamycin | 200 | 200 | 0.39 | 1.56 | 50 |
