Fig. 7: Peptide-induced transcriptional changes in MRSA USA300 cells. | npj Biofilms and Microbiomes

Fig. 7: Peptide-induced transcriptional changes in MRSA USA300 cells.

From: In silico identification of two peptides with antibacterial activity against multidrug-resistant Staphylococcus aureus

Fig. 7

a Principal component plot and b Hierarchical clustering analysis plot in the HG2 treatment group after outlier(s) (HG2_1 and Untreated2_1) removal. c Principal component plot and d Hierarchical clustering analysis plot in the HG4 treatment group after outlier (Untreated_3) removal. Frequencies of top ten Gene Ontology (GO) terms in the DEGs in samples treated with e HG2 and f HG4. In total, 12 samples were sequenced (six per HG2 treatment group i.e., HG2_1, HG2_2, HG2_3, Unt_1, Unt_2 and Unt_3 and six per HG4 treatment group including HG4_1, HG4_2, HG4_3, Unt_1, Unt_2 and Unt_3). As the HG2 treatment experiment, was performed separately from the HG4 treatment experiment with each group having their own distinct untreated sample groups, the analysis of each treatment group was performed separately.

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