Fig. 3: Secretome analysis of mature C. albicans biofilm media.
From: Impaired amino acid uptake leads to global metabolic imbalance of Candida albicans biofilms
a Volcano plot illustrating the log2 ratio of secreted proteins in 48 and 24 h biofilms to the corresponding padj value (−log10). Dashed lines symbolize the cutoff (p < 0.05 and log2FC ± 2). A total of 1103 different proteins were identified in all biofilms examined, with 801 proteins detected at 24 h and 1067 proteins detected at 48 h. Only 14% contained a signal peptide (SP) for directed secretion. Both the fraction with and without SP showed higher protein quality after 48 h. b GO term analysis of all detected proteins containing an SP. Counts represent observed protein abundance compared to the number of proteins assigned to the term (size). Results for molecular function and biological process were each summarized using REVIGO with a cutoff of 0.5 dispensability. Source data are provided as a Source Data file.
