Fig. 3: Correlation network of colorectal cancer gut mucosal microbiomes.
From: Tumour microbiomes and Fusobacterium genomics in Vietnamese colorectal cancer patients
The network was constructed from 117 most representative ASVs sampled from 86 mucosal microbiomes, outlining significant interactions detected by both CCLasso (p value ≤ 0.01 and absolute correlation strength > 0.37) and SpiecEasi. Positive and negative interactions were coloured as red and blue lines respectively, with line weight proportional to correlation strength. The ASVs (nodes) were coloured based on taxonomic family (see Legend), with sizes proportional to their relative abundances. The light green shaded area entails ASVs identified as members of the human oral microbiome (comparison with expanded Human Oral Microbiome Database); the blue shaded area covers ASVs identified as gut anaerobic commensals (Lachnospirales, Bacteroidales, Bifidobacteriales, Oscillospirales); and gray shaded area covers other tumour-associated ASVs (as identified in Fig. 2a). Source data are provided as a Source Data file.
