Fig. 7: Metabolomics identifies pediatric-specific pathways that restore independently of adult donor engraftment. | npj Biofilms and Microbiomes

Fig. 7: Metabolomics identifies pediatric-specific pathways that restore independently of adult donor engraftment.

From: Donor-recipient specificity and age-dependency in fecal microbiota therapy and probiotic resolution of gastrointestinal symptoms

Fig. 7

A Metabolite set enrichment analysis identifies significant metabolic pathways that are conserved in healthy children (HC and PostFMT). Top 5 pathways that differentiate healthy pediatric from adult donors are highlighted (red). B Branched-chain amino acid degradation is significantly elevated in post-FMT and healthy children. Kruskal-Wallis test with BH procedure for donor, PostFMT (β1 > 0.6) and HC samples: *p < 0.05. Denotations: BCAT branched-chain aminotransferase, BCKD branched chain ketoacid dehydrogenase.

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