Table 1 Cohort sample sizes across time points for fecal diversity or differential abundance analyses.

From: Oral and middle ear delivery of otitis media standard of care antibiotics, but not biofilm-targeted antibodies, alter chinchilla nasopharyngeal and fecal microbiomes

Fecal diversity analysis

Baseline

2DPT

5DPT

7DPT

9DPT

Fecal differential abundance analysis

Baseline

2DPT

5DPT

7DPT

9DPT

AC-PO7d

3

2

3

3

2

AC-PO7d

3

2

3

3

2

AC-10 mg/kg

2

2

2

1

2

AC-10 mg/kg

2

3

2

1

2

AC-5 mg/kg

2

2

3

3

3

AC-5 mg/kg

2

3

3

3

3

Anti-rsPilA

3

3

2

2

2

Anti-rsPilA

3

3

2

2

2

Anti-tip-chimer

3

3

3

2

3

Anti-tip-chimer

3

3

3

3

3

Ofloxacin

3

2

3

3

3

Ofloxacin

3

3

3

3

3

TS-30 mg/kg

3

3

3

3

3

TS-30 mg/kg

3

3

3

3

3

TS-15 mg/kg

3

3

3

3

3

TS-15 mg/kg

3

3

3

3

3

Saline

3

3

3

2

1

Saline

3

3

3

3

2

  1. All cohorts started with three chinchillas. Decreases in cohort size were due to failure to collect a sample, humane endpoint euthanasia or mortality, or rarefaction criteria (diversity analyses).