Fig. 7: Molecular model depicting the mechanism of hsa-miR-7704 exacerbation of HE through inhibition of B. longum. | npj Biofilms and Microbiomes

Fig. 7: Molecular model depicting the mechanism of hsa-miR-7704 exacerbation of HE through inhibition of B. longum.

From: Faecal hsa-miR-7704 inhibits the growth and adhesion of Bifidobacterium longum by suppressing ProB and aggravates hepatic encephalopathy

Fig. 7

Faecal hsa-miR-7704 enriched in patients with HE inhibits the growth and adhesion of B. longum by suppressing proB. Reduction of acetate results in overactivation of microglia and hyperammonaemia, thus inhibiting neuronal activity and aggravating HE.

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