Fig. 4: Comparison of control-enriched and disease-enriched species between diseased and control individuals.

Case-control comparisons with a significance different of gross relative abundance between patients and controls are highlighted. Boxes represent the interquartile range between the first and third quartiles and the median (internal line). Whiskers denote the lowest and highest values within 1.5 times the range of the first and third quartiles, respectively; dots represent outlier samples beyond the whiskers. Wilcoxon rank-sum test: *p < 0.05; **p < 0.01; ***p < 0.001.