Fig. 6: Spatial distribution of the gut microbial community resulting from ABM simulations of a multi-species biofilm on a modeled intestinal niche.

(Upper) A highly cross-feeding community, including three species in bidirectional cross-feeding and two species in unidirectional (commensal) cross-feeding. Most bacterial species are inter-dispersed. Also, see Supplementary Fig. 12 for schematics showing detailed bacterial relationships and further details. (Middle) A community featuring one cross-feeding pair, one competitive pair, and a neutralistic species. The competitive bacteria, which grow more slowly, are outcompeted. (Lower) A purely competitive community. The dispersion, especially at the upper growth front, is relatively small. The right-hand side heatmaps show the segregation index matrix for each type of interaction (for the definition of segregation matrix refer to “Methods”).