Fig. 9 | npj Biofilms and Microbiomes

Fig. 9

From: Mechanisms of S. agalactiae promoting G. vaginalis biofilm formation leading to recurrence of BV

Fig. 9

Interaction mechanism in GBS and GV dual-species biofilm (SAM: S-Adenosyl methionine): In GBS and GV dual-species biofilms, GBS enhanced the expression of luxS genes and produced large amounts of AI-2 by sensing the increase in GV density. GV, upon receiving the AI-2 signals, up-regulate the expression of murG and GAVG_RS05105 genes, which promotes biofilm formation, thus affecting the recurrence of BV.

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