Fig. 3: Distribution of Streptococcus clades in ancient dental calculus samples from Middenbeemster, the Netherlands and canonical correlations with sample parameters.

A Percent of Streptococcus reads that were assigned to each clade out of all reads assigned to Streptococcus, ordered by decreasing relative abundance of Sanguinis clade and increasing relative abundance of Anginosus clade. B Percent of reads assigned to species in the genus Streptococcus and to all other genera. C Percent of reads assigned to species in the Sanguinis and Anginosus clades out of all species-level read assignments. D Canonical correlations between the percent of Sanguinis clade or Anginosus clade (from A) and archeological metadata, laboratory, and sequencing metrics.