Fig. 2: Distribution of NEVs in biological organisms. | npj Biofilms and Microbiomes

Fig. 2: Distribution of NEVs in biological organisms.

From: Bifidobacterium longum NSP001-derived extracellular vesicles ameliorate ulcerative colitis by modulating T cell responses in gut microbiota-(in)dependent manners

Fig. 2

A Representative images of whole-body live imaging in mice at different time points (n = 3). B Representative fluorescent images of the mouse gastrointestinal tract at different time points (n = 3). C, D Quantitative fluorescence statistics of mouse gastrointestinal tract and colon at different time points (n = 3). E Whole-body and gastrointestinal tract fluorescence images of normal and DSS-induced colitis mice at 18 h (n = 3). F, G Gastrointestinal tract and colon fluorescence quantitative data plots of normal and DSS-induced colitis mice at 18 h (n = 3). H–J FACS was used to determine the population of cells to uptake AF647-labeled NEVs (n = 5). Data were shown as means ± SEM. Significance was assessed using Student’s t-test, giving P values: *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001. NEVs B. longum NSP001 extracellular vesicles, DSS dextran sulfate sodium, FACS fluorescence-activated cell sorting.

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