Fig. 4: The significantly different functional pathways between MRS-Low and MRS-moderate/high patients and their associations with identified prognostic species.
From: Oral microbiota signature predicts the prognosis of colorectal carcinoma
A Heatmap of Spearman correlation between prognostic species and differential pathways. The KEGG pathways were predicted using PICRUSt2 to infer the functional shifts in the microbiota of MRS-Low and MRS-moderate/high patients. The strength of the color depicted Spearman’s correlation coefficients (negative correlation, blue; positive correlation, red). (*P < 0.05). B The differential analysis of the oral microbial community’s functions between MRS-moderate/high and MRS-low groups, using STAMP software. The analysis focused on KEGG pathways with an average relative abundance exceeding 1%, and the P value is corrected using the Bonferroni method. The difference in mean proportion for pathways showing significant differences in abundance was shown. The 95% confidence intervals and statistical significance (P value corrected) were indicated as well.
