Fig. 6: PICRUSt2 pathways associated with tumors, biofilms, and Fna C2 abundance.
From: Fusobacterium nucleatum is enriched in invasive biofilms in colorectal cancer
A Heatmap of all statistically significant PICRUSt2 pathways with differences in gene content between tumor (n = 112) and normal (n = 112) samples for either biofilm-positive tissues (left) or biofilm-negative tissues (right), as analyzed by Mann Whitney test, with p < 0.05 considered significant. Data depicted as Log2 Fold Change between tumor and normal samples (>0 indicates higher in tumor). B For each indicated comparison, the listed pathways are the 4 PICRUSt2 pathways with the greatest Log2 Fold Change between groups. For each pathway, the genera listed are the top 3 taxa contributing to enrichment of that pathway. See Figs. S12, S13, and S14A for the full display of significantly enriched or depleted pathways for each comparison. See Table S4 for all taxa significantly contributing to each enriched pathway.
