Fig. 5: Bacterial OTU co-occurrence network and module-trait associations. | npj Biofilms and Microbiomes

Fig. 5: Bacterial OTU co-occurrence network and module-trait associations.

From: Di (2-ethylhexyl) Phthalate decrease pregnancy rate via disrupting the microbe-gut-hypothalamic-pituitary-ovarian axis in mice

Fig. 5

Co-occurrence networks of Control group (A) and DEHP treatment (B) with OTU (nodes) colored according to the phyla to which they belong. Any resulting correlations with p value ≥ 0.01 and abs(r) <0.3 were removed. Green lines with different thicknesses were drawn by the weight of the edges. Module-trait associations between one OTU module with a HPO axis-related hormones trait or mouse pregnant rate are shown by color blocks (red for positive correlations and blue for negative correlations) which contain the correlation and the corresponding p value (*p < 0.05; **p < 0.01; ***p < 0.001). C Cumulative relative abundances of phyla in Control and DEHP networks. D Heatmaps showing the normalized relative abundances of shared and unique bacterial OTUs between Control and DEHP networks.

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