Fig. 4: Integrated evaluation of host DNA depletion methods. | npj Biofilms and Microbiomes

Fig. 4: Integrated evaluation of host DNA depletion methods.

From: Benefits and challenges of host depletion methods in profiling the upper and lower respiratory microbiome

Fig. 4

Radar charts showing the performance of host DNA depletion methods on five evaluation metrics in BALF (A) and OP (B) samples. Accuracy was defined as 1 subtracted by the JSD between microbial compositions of different methods and R_ase. The contamination level was defined as 1 subtracted by the proportion of contaminants in total microbial reads. Microbial proportion and accuracy were estimated excluding exogenous contamination. Maximum-minimum measures were used for data scaling. The two methods with the best performance (largest radar area) are labeled in bold. n = 35 for BALF and n = 34 for OP.

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