Fig. 2: Weighted correlation gene network analysis reveals module associations with disease.

A Module trait relationship heatmap with correlation and p-values for each module. Modules are sorted from left to right (healthy to Parkinson’s disease) based on the eigenvector value. The top panel represents the number of genes belonging to each module. B Network topology analysis for the modules grouped by trait association. A Kruskal and Wallis test was performed according to the trait association to compare modules based on their associations or not to one of the two groups. C Correlation between module diversity and other topology features. Correlation tests are spearman tests.