Fig. 4: Vaginal Microbiome Community State Types (CSTs) according to blood group in women at risk of preterm birth.

a Proportions of CST I-V in women defined as being at risk of preterm birth by ABO blood group phenotype at timepoint 1 (12+0–15+6), b and at timepoint 2 (20+0–23+6). c Proportions of CST1-V in women categorised by risk factors of previous cervical treatment (CT) or previous preterm birth of mid-trimester loss (pPTB/ MTL) and by ABO blood group phenotype at timepoint 1 (12+0–15+6) and at (d) timepoint 2 (20+0-23+6). Proportions of CST I-V at timepoint 1 (12 + 0-15 + 6) in women categorised by outcomes of cervical length and pregnancy outcome in women with blood group (e) A, (f) B and (g) O. Comparisons made using Chi-squared and adjusted for multiple comparisons. P value significance: *<0.05, **<0.01, ***<0.001, ****<0.0001.