Fig. 8: Enhanced anti-tumor immune response by gut microbiota and short-chain fatty acids (SCFAs). | npj Biofilms and Microbiomes

Fig. 8: Enhanced anti-tumor immune response by gut microbiota and short-chain fatty acids (SCFAs).

From: Gut microbiota and SCFAs improve the treatment efficacy of chemotherapy and immunotherapy in NSCLC

Fig. 8

A, B Flow cytometry to detect the immune cells in the spleen and tumors (n = 5 per group). Infiltration of CD45+ T cells, CD3+ T cells, CD8+ T cells, and the expression of tumor necrosis factor-α (TNF-α), granzyme B (GZMB) among CD8+ T cells in the spleen and tumor tissue. C interferon-γ (IFN-γ), interleukin-2 receptor (IL-2Rα), interleukin-6 (IL-6), and interleukin-10 (IL-10) levels in blood were detected by enzyme-linked immunosorbent assay (ELISA). Data represent the mean ± standard deviation (SD) and were analyzed by one-way analysis of variance (ANOVA). *P < 0.05, ** P > 0.01, ***P > 0.001, **** P < 0.0001.

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