Fig. 2: Lactobacillus and Bifidobacterium represent differential taxonomies in the gut microbiome of healthy individuals, Carbapenem-resistant Klebsiella pneumoniae (CRKP) intestinal colonization-positive ICU patients, and CRKP intestinal colonization-negative ICU patients. | npj Biofilms and Microbiomes

Fig. 2: Lactobacillus and Bifidobacterium represent differential taxonomies in the gut microbiome of healthy individuals, Carbapenem-resistant Klebsiella pneumoniae (CRKP) intestinal colonization-positive ICU patients, and CRKP intestinal colonization-negative ICU patients.

From: Microbiome-mediated colonization resistance to carbapenem-resistant Klebsiella pneumoniae in ICU patients

Fig. 2

A The gut microbiome of healthy individuals (HCG) and ICU patients (ICU-A) displays difference in the composition of gut microbiome at genus level. B The gut microbiome of CRKP-negative patients (CRKP-N) and their admission samples (CRKP-NA), CRKP-positive patients (CRKP-P), and their corresponding baseline samples upon admission (CRKP-PA) at the genus level. C–F Lefse analysis identified differential genera between HCG and ICU-A (C), CRKP-P and CRKP-N (D), CRKP-P and CRKP-PA (E), and CRKP-PA vs. CRKP-NA (F). G Sankey diagrams provided a more intuitive visualization, showing significant differences in Klebsiella between CRKP-PA and CRKP-P, while no significant changes were observed between CRKP-NA and CRKP-N. H The abundance of Bifidobacterium longum significantly decreased in CRKP-P compared with CRKP-PA. I Lactiplantibacillus plantarum abundance was significantly decreased in the CRKP-P compared with the CRKP-N. The Kruskal–Wallis test was used for significance testing.

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