Fig. 2
From: Human snoRNA-93 is processed into a microRNA-like RNA that promotes breast cancer cell invasion
Tools for manipulating sdRNA-93 expression. a The most thermodynamically stable secondary structure of snoRNA-93 as calculated by Mfold.53 Predominately excised sdRNA-93 sequence is highlighted in green. b Knockdown of sdRNA-93 by transient transfection of MDA-MB-231 cells with custom inhibitor (antisense to sdRNA-93) sequence depicted in green in a as determined by RT-qPCR (n = 3). c Small transcript northern blot confirming the over expression of sdRNA-93 following transfection of MDA-MB-231 cells with custom mimic (identical to sdRNA-93 sequence depicted in green in a vs. scrambled control (ctl))
