Table 1 Baseline patient and tumor characteristics
All patients | RS < 11 | RS: 11-<18 | RS: 18–25 | RS: 26–30 | RS ≥ 31 | |
|---|---|---|---|---|---|---|
N = 1801 | n = 304 | n = 576 | n = 562 | n = 171 | n = 188 | |
Gender, n (%) | ||||||
Female | 1787 (99) | 301 (99) | 573 (99) | 558 (99) | 169 (99) | 186 (99) |
Male | 14 (<1) | 3 (1) | 3 (1) | 4 (1) | 2 (1) | 2 (1) |
Age | ||||||
Median (interquartile range), years | 60 (52–67) | 63 (56–71) | 59 (51–66) | 59 (53–66) | 60 (54–66) | 59 (50–66) |
Mean (SD), years | 59.4 (10) | 62.9 (10) | 58.7 (10) | 58.9 (9) | 59.7 (10) | 57.6 (12) |
Age category, n (%) | ||||||
<40 years | 47 (2.6) | 3 (1) | 7 (1) | 15 (3) | 4 (2) | 18 (10) |
40–49 years | 248 (13.8) | 31 (10) | 96 (17) | 74 (13) | 20 (12) | 27 (14) |
50–59 years | 580 (32.2) | 67 (22) | 204 (35) | 199 (35) | 59 (35) | 51 (27) |
60–69 years | 604 (33.5) | 113 (37) | 178 (31) | 198 (35) | 59 (35) | 56 (30) |
70–79 years | 295 (16.4) | 81 (27) | 80 (14) | 72 (13) | 27 (16) | 35 (19) |
≥80 years | 27 (1.5) | 9 (3) | 11 (2) | 4 (1) | 2 (1) | 1 (0) |
Tumor size in the greatest dimension | ||||||
Median (interquartile range), cm | 1.5 (1.1, 2.0) | 1.5 (1.1–2.0) | 1.5 (1.0–2.0) | 1.5 (1.0–2.0) | 1.5 (1.2–2.0) | 1.8 (1.5–2.5) |
Mean (SD), cm | 1.7 (0.8) | 1.6 (0.8) | 1.6 (0.8) | 1.6 (0.8) | 1.7 (0.8) | 2.0 (0.9) |
Tumor size category, n (%) | ||||||
≤1 cm | 400 (22.2) | 63 (21) | 143 (25) | 140 (25) | 32 (19) | 22 (12) |
>1–2 cm | 996 (55.3) | 181 (60) | 320 (56) | 302 (54) | 103 (60) | 90 (48) |
>2–3 cm | 313 (17.4) | 48 (16) | 84 (15) | 94 (17) | 28 (16) | 59 (31) |
>3 | 80 (4.4) | 11 (4) | 24 (4) | 23 (4) | 7 (4) | 15 (8) |
Unknown | 12 (0.7) | 1 (0) | 5 (1) | 3 (0) | 1 (1) | 2 (1) |
Tumor grade category, n (%) | ||||||
Grade 1 | 258 (14.3) | 61 (20) | 109 (19) | 73 (13) | 10 (6) | 5 (3) |
Grade 2 | 907 (50.4) | 173 (57) | 291 (51) | 283 (51) | 80 (47) | 80 (43) |
Grade 3 | 297 (16.5) | 15 (5) | 56 (10) | 93 (17) | 48 (28) | 85 (45) |
Not applicable/Unknowna | 339 (18.8) | 55 (18) | 120 (21) | 113 (20) | 33 (19) | 18 (10) |
Tumor grade and size, n (%) | ||||||
Grade 1 and tumor size ≤1 cm | 90 (4.9) | 15 (5) | 44 (8) | 28 (5) | 3 (2) | 0 (0) |
Histology, n (%) | ||||||
IDC | 1461 (81.1) | 274 (81) | 451 (78) | 454 (81) | 139 (81) | 170 (90) |
ILC | 213 (11.8) | 23 (8) | 80 (14) | 78 (14) | 23 (14) | 9 (5) |
Mucinous/colloid | 53 (2.9) | 14 (4) | 20 (4) | 13 (2) | 5 (3) | 1 (1) |
Papillary | 21 (1.2) | 10 (3) | 6 (1) | 3 (1) | 0 (0) | 2 (1) |
Other | 53 (2.9) | 10 (3) | 19 (3) | 14 (2) | 4 (3) | 6 (3) |
