Fig. 2

AR expression is predictive of response to radiation. Kaplan–Meier local recurrence-free survival analysis in the Servant data set demonstrates that patients with TNBC whose tumors have higher than median expression of AR (red line) have significantly higher rates of local recurrence after radiation and an overall poorer prognosis than patients with lower than median expression (black line) of AR (a). In patients with TNBC who did not receive radiation treatment, there was no difference in local recurrence depending on higher (red line) or lower (black line) than median expression of AR (b). Receiver operator curve analysis in the Servant data set demonstrates that AR expression level with the highest AUC value (0.69) when compared against other clinicopathologic parameters (c). In multivariable Cox regression analysis in the Servant data set, only AR expression remained significantly associated with worse local recurrence-free (LRF) survival (d). Hazards ratios, 95% confidence intervals, and p-values were calculated for all analyses and are listed