Fig. 4 | npj Breast Cancer

Fig. 4

From: Breast cancer diagnosed during pregnancy is associated with enrichment of non-silent mutations, mismatch repair deficiency signature and mucin mutations

Fig. 4

Association of signature 20 with mutational load and clinical outcome. a Comparison of SNV mutational load between Sig20 negative and Sig20 positive tumors. b Comparison of MSH2 expression between Sig20 negative and Sig20 positive tumors. c Kaplan–Meier plot showing the difference in DFS between control patients (N = 18), BCP patients with Sig20 negative tumors (N = 22) and BCP patients with Sig20 positive tumors (N = 13). P, p-value derived for the Mann–Whitney U test

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